Motor Neurone Disease Appeal

Motor Neurone Disease Appeal

Posted on 22nd November 2018

Funding Neuro | MND

Motor Neurone Disease MND

This campaign will lay the foundations for human trials of a pioneering therapy for Motor Neurone Disease (MND). The fatal disease affects the brain and nerves and causes weakness over time.  There is currently no cure for the condition.

The work led by Bristol-based neurosurgeon Professor Steven Gill combines three elements.  Gene Therapy with Viral Vectors delivered via Convection Enhanced Delivery CED.  

It is known that specific viruses can have a therapeutic effect on motor neurons. With a technique called Convection Enhance Delivery (CED). This is able to deliver these viruses directly to the neurons in the brain. Drug delivery to affected neurons, to correct or repair defects has been a major challenge.

Professor Gill is known for his pioneering work with delivering drugs directly into the brain with CED to treat Parkinson’s Disease and brain tumours. Professor Gill has conducted a number of pre-clinical tests with gene therapy targeting Motor Neurone Disease.

The tests have shown promising results. The next ‘pre-clinical’ stage is to evaluate the safety and efficacy of the treatment. This crucial phase must be completed before clinical trials in humans can be started.

Professor Steven Gill said: “The standard treatments that are currently available for Motor Neurone Disease may enhance a patient’s quality of life but there is yet to be a therapy to combat the disease. Backed by Funding Neuro, our project has the potential to offer a fast track approach to a neuroprotective and regenerative treatment for the disease.

Listen to Ian Bains Story….


Donating to the appeal is quick and simple


JustGiving – mnd appeal

Thank you for your support.

If you have any questions regarding this appeal please contact our office on 0141 465 6840


Our esteemed supporters
Funding Neuro supporter